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WG 3: Disease-specific MRCs

Main objective: Comparative analysis of MRCs obtained from patients with different diseases in order to define common and disease-specific features of MRCs. This task will be performed in close collaboration with and by using results obtained in WG 1 and WG 2. 

Methods and means:

  • Generation of a task force with the aim to identify diseases and patient cohorts for the analysis of disease-specific (and common) features of MRCs.
  • Contact with WG 1 and WG 2 on the selection of markers and analytical tools.
  • Definition of SOPs for the collection, storage and analysis of data (together with members from WG 1 and WG 2).
  • Comparative analysis of MRCs according to the main objective of this WG 3.
  • Based on the expertise and composition of the Action during the planning phase, WG 3 will start with material from cancer patients and patients with viral infection. The programme of WG 3 remains flexible so as to be able to incorporate new scientific developments and incoming network participants.
  • Validated guidelines and SOPs will be implemented into clinical immunomonitoring protocols operative at the partner sites.