Baran, Jarek

Models available:

Gastric cancer, colon cancer, NOD-SCID mouse model of human tumuor xenografts, human samples (blood, bone marrow), macrophage polarization after contact with tumour-derived microvesicles

Cells available:

Monocytes, macrophages, dendritic cells

Technology available:

10-colour flow cytometry analysis and 9-colour flow cytometry cell sorting; nanoparticle tracking analysis; cellular immunology

Key publications related to Mye-EUNITER:

  1. Stec M.*, Baran J.*, Szatanek R., Mytar B., Lenart M., Czupryna A., Szczepanik A., Siedlar M., Zembala M. Properties of monocytes generated from haematopoietic CD34+ stem cells from bone marrow of colon cancer patients. Cancer Immunol. Immunother. 2013, 62: 705-13.; * equal contribution

  2. Stec M, Baran J, Szatanek R, Mytar B, Baj-Krzyworzeka M, Gozdzik J, Siedlar M, Zembala M. Interactions of monocyte subpopulations generated from cord blood CD34+ haematopoietic progenitors with tumor cells: assessment of antitumour potential. Exp. Hematol. 2012, 40: 914-21.

  3. Baran J, Baj-Krzyworzeka M, Weglarczyk K, Szatanek R, Zembala M, Barabasz J, Czupryna A, Szczepanik A, Zembala M. Circulating tumour-derived microvesicles in plasma of gastric cancer patients Cancer Immunol Immunother. 2010, 59(6):841-50.

  4. J.Więckiewicz, B.Mytar, R.Szatanek, K.Węglarczyk, J.Baran: „Induction of monocyte antitumour response by human cancer cells transduced with TNF-GFP fusion gene – possible implications for immunotherapy of cancer”. Folia Histochemica et Cytobiologica, 2011, 49, 512.

  5. M.Baj-Krzyworzeka, R.Szatanek, K.Węglarczyk, J.Baran, M.Zembala: ”Tumor-derived microvesicles modulate biological activity of human monocytes”. Immunology Letters, 2007, 113, 76.