Mye-EUNITER
 

Dev, Kumlesh K.

Models available:

  • Neuroinflammation, demyelinating diseases, multiple sclerosis, schizophrenia
  • S1P receptors, cytokines

Cells available:

  • Astrocyte communication with immune cells, oligodendrocyte demyelination,

Key publications related to Mye-EUNITER:

  1. A.J. Pritchard, A.K. Mir, K.K. Dev (2014) S1P receptor modulation attenuates splenocyte-induced demyelination in cerebellar slice cultures. PLoS ONE, 9, e99444.

  2. G. Elain, K. Jeanneau, A. Rutkowska, A.K. Mir, and K.K. Dev (2014). The Selective Anti-IL17A Monoclonal Antibody Secukinumab (AIN457) Attenuates IL17A-Induced Levels of IL6 in Human Astrocytes. Glia, 62, 725-735. 

  3. G.K. Sheridan, K.K. Dev (2014) Targeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations. Scientific Reports, 23, 5051.

  4. K.E. O’Connell, T.H. Mok, B. Sweeney, A. Ryan, K.K. Dev (2014). Cytokine signature patterns in patients with Multiple Sclerosis. Autoimmunity, 30, 1-7.

  5. G.K. Sheridan, K.K. Dev (2012). The S1P1 receptor subtype inhibits demyelination and regulates chemokine release in cerebellar slice cultures. Glia, 60, 382-392.

Contact details:

Drug Development
School of Medicine
Trinity College Dublin
Dublin
Ireland
Tel.: +353 1 896 4180
E-mail: devk@tcd.ie