Oral, H. Barbaros

Barbaros Oral studied medicine at the Uludag University Faculty of Medicine, Bursa, Turkey (1982-1988). He became a specialist in Infectious Diseases and Clinical Microbiology at the same university in 1998. He obtained his MSc and Ph.D. (1992-1997) at the Imperial College of Science, Technology and Medicine, the University of London, UK. He has been a professor at Uludag University since 2008. Prof. Oral have published over 50 papers in peer-reviewed journals and various book chapters in the fields of microbiology and immunology.He was also on the editorial and reviewer boards of several scientific journals. His main research interests include gene and/or dendritic cell-based treatment of autoimmune and inflammatory diseases, including rheumatoid arthritis and psoriasis. 

Models available:

Genetically modified dendritic cells, mouse arthritis model (CIA), mouse psoriasis model

Cells available:

Dendritic cells, Myeloid-derived suppressor cells, Macrophages

Technology available:

  • Flow cytometry

  • Luminex

  • Cell culturing

  • Real-time PCR

  • Western  blot

Key publications related to Mye-EUNITER:

  1. Oral, H.B., D.F.P. Larkin, Z. Fehervari, A. Byrnes, A. Rankin, D.O. Haskard, M.J.A. Wood, M.J. Dalmann, A.J.T. George. Ex vivo adenovirus-mediated gene transfer and immunomodulatory protein production in human cornea. Gene  Therapy, 4, 639-647  (1997).
  2. Oral, H.B., S.V. Kotenko, M. Yılmaz, O. Mani, J. Zumkehr, K. Blaser, A.C. Akdis, M. Akdis. Regulation of T cells and cytokines by interleukin-10-family cytokines IL-19, IL-20, IL-22, IL-24 and IL-26. Eur. J. Immunol. 36, 380-388 (2006).          
  3. Budak, F., G. Göral, Y. Heper, E. Yılmaz, F. Aymak, B. Baştürk, O. Töre, B. Ener, H.B. Oral. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis. CYTOKINE 38, 32-36 (2007).
  4. Yucel, A., K. Dilek, D. Saba, A.A. Özçimen, M. Yurtkuran, H.B. Oral. Interleukin-2 gene polymorphisms in Turkish patients with Behçet's Disease and its associatıon with ocular involvement. Int J Immunogenet. 40: 349-55 (2013).
  5. Oğuz Ayarcı, A., E. Yılmaz, D. Sığırlı, F. Budak, G. Göral, H.B. Oral. Diagnostic Value of  Serum High Mobility Group Box Protein 1 and Soluble CD163 Levels in Brucellosis. Microbiol Immunol. 57:150-8 (2013).