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As part of this process, instead of fighting disease, immune cells.

Post-Doctoral Fellowship in Immuno-oncology, Jeff Pollard’s lab, University of Edinburgh

Dr Jeff Pollard at the Medical Research Council - Centre for Reproductive Health, University of Edinburgh who has pioneered the role of macrophages in tumour progression is seeking post-doctoral fellows to explore the mechanism of immunosuppression in tumours. The candidate will use pioneering new mouse immune-reporter models and human induced pluripotent stem cell derived macrophage models to explore the role of myeloid cells in regulating T cell activity. The applicant must have thorough training in T cell immunology in any field and be cognisant of the challenges of studying immune response in vivo.

The lab is fully supported in the modern research facility on the BioQuarter site in Edinburgh next to the major hospitals with extensive research facilities including excellent FACS, live optical imaging, genomic and proteomic facilities. Grant funding extends to 2024.

Please send responses to and directly to jeff.pollard@ed.ac.uk. Accompanied by a cv, and names of three referees.

Relevant publications:

  1. Cassetta L, et al. (2019) Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets. Cancer cell 35(4):588-602 e510.
  2. Kitamura T, et al. (2017) Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer. Frontiers in immunology 8:2004.
  3. Cassetta L & Pollard JW (2018) Targeting macrophages: therapeutic approaches in cancer. Nat Rev Drug Discov 17:887 - 904.